Molekulare Orthopädie

  1. Baltzer AW, Ostapczuk MS, Stosch D, Seidel F, Granrath M. A new treatment for hip osteoarthritis: clinical evidence for the efficacy of autologous conditioned serum. Orthop Rev (Pavia). 2013 Jun 14;5(2):59-64 http://www.ncbi.nlm.nih.gov/pubmed/23888203

  2. Baltzer AWA, Ostapczuk MS, Stosch D, Granrath M. (2012) The use of rhBMP-2 for the treatment of a delayed union following femoral neck open-wedge osteotomy. Orthopaedic Reviews 4:e4 http://www.pagepress.org/journals/index.php/or/article/view/or.2012.e4

  3. Baltzer AW, Moser C, Jansen SA, Krauspe R. Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis. Osteoarthritis Cartilage. 2009 Feb;17(2):152-60. http://www.oarsijournal.com/article/S1063-4584(08)00209-4/abstract

  4. Wehling P, Reinecke J, Baltzer AW, Granrath M, Schulitz KP, Schultz C, Krauspe R, Whiteside TW, Elder E, Ghivizzani SC, Robbins PD, Evans CH. Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis. Hum Gene Ther. 2009 Feb;20(2):97-101. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855248/?tool=pubmed

  5. Schoch B, Regel JP, Nierhaus A, Wichert M, Mueller OM, Sandalcioglu IE, Mann K, Stolke D. Predictive value of intrathecal interleukin-6 for ventriculostomy-related Infection. Zentralbl Neurochir. 2008 May;69(2):80-6. https://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-1022559

  6. Schoch B, Regel JP, Wichert M, Gasser T, Volbracht L, Stolke D. Analysis of intrathecal interleukin-6 as a potential predictive factor for vasospasm in subarachnoid hemorrhage. Neurosurgery. 2007 May;60(5):828-36; discussion 828-36. http://journals.lww.com/neurosurgery/pages/articleviewer.aspx?year=2007&issue=05000&article=00004&type=abstract

  7. Egermann M, Baltzer AW, Adamszek S, Evans CH, Robbins P, Schneider E, Lill CA (2006) Direct Adenoviral Transfer of Bone Morphogenetic Protein-2 cDNA Enhances Fracture Healing in Osteoporotic Sheep. Hum Gene Ther 17: 507-517 http://www.liebertonline.com/doi/abs/10.1089/hum.2006.17.507?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dncbi.nlm.nih.gov

  8. Sandalcioglu IE, Wende D, Eggert A, Regel JP, Stolke D, Wiedemayer H. VEGF plasma levels in non-ruptured intracranial aneurysms. Neurosurgical Review 2006 Jan;29(1):26-9. . http://www.springerlink.com/content/k8053x36804q71t8/

  9. Moser C, Baltzer AWA, Reinecke J, Wehling P (2005) Die Rolle der Zytokine bei Knorpeldefekten und in der Knorpeltherapie ? Interleukin-I und TNF alpha: Schlüsselfaktoren der Knorpeldestruktion. Arthoskopie 18:181-185

  10. Egermann M, Schneider E, Evans CH, Baltzer AW (2005) The potential of gene therapy for fracture healing in osteoporosis. Osteoporos Int 16 Suppl 2: S120-8 http://www.ncbi.nlm.nih.gov/pubmed/15654580

  11. Liebau C, Roesel C, Schmidt S, Karreman C, Prisack JB, Bojar H, Merk H, Neumann W, Baltzer AW (2004) Immunotherapy by gene transfer with plasmids encoding IL-12/IL-18 is superior to IL-23/IL-18 gene transfer in a rat osteosarcoma model. Anticancer Res. 24(5A):2861-7 http://www.ncbi.nlm.nih.gov/pubmed/15517889

  12. Lattermann C, Baltzer AW, Zelle B, Whalen JD, Nijibizi C, Robbins PD, Evans CH, Gruen G (2004) Feasibility of percutaneous gene transfer to an atrophic nonunion in a rabbit. Clin Orth Rel Res 425: 237-243 http://ovidsp.tx.ovid.com/sp-3.2.2/ovidweb.cgi?T=JS&PAGE=fulltext&D=ovft&AN=00003086-200408000-00034&NEWS=N&CSC=Y&CHANNEL=PubMed

  13. Lattermann C, Zelle BA, Whalen JD, Baltzer AW, Robbins PD, Niyibizi C, Evans CH, Fu FH (2004) Gene transfer to the tendon-bone insertion site. Knee Surg Sports Traumatol Arthrosc. 12: 510-515 http://www.springerlink.com/content/7lu84n2h8x7cbcry/

  14. Baltzer AW, Lieberman J (2004) Regional gene therapy to enhance bone repair. Gene Ther, 11:344-50 http://www.ncbi.nlm.nih.gov/pubmed/14724686

  15. Liebau C, Merk H, Schmidt S, Roesel C, Karreman C, Prisack JB, Bojar H, Baltzer AWA (2003) IL-12 and IL-18 change ICAM-I expression , and enhance NK cell mediated cytolysis of human osteosarcoma cells. Cytokines, Cellular & Molecular and Therapy, 7: 135-142

  16. Baltzer AWA (2003) Zum Nebenwirkungsprofil Nicht-Steroidaler Antirheumatika (NSAR) bei der Therapie von Erkrankungen des Bewegungsapparates (2003) Z Orthop 141: Oa369-371

  17. Baltzer AW, Drewer R, Granrath M, Godde G, Klein W, Wehling P (2003) Intraartikuläre Therapie der Gonarthrose mit autologem Interleukin-I Rezeptor Antagonisten (IL-1 Ra). Deut Zeitschr Sportmed 54: 209-211 http://www.zeitschrift-sportmedizin.de/Inhalt/images/heft0603/a12_0603.pdf

  18. Rebmann V, Regel JP, Stolke D, Grosse-Wilde H: Secretion of sHLA-G molecules in malignancies. Semin Cancer Biol. 2003 Oct;13(5):371-7. http://www.ncbi.nlm.nih.gov/pubmed/14708717

  19. Liebau C, Merk HR, Roesel C, Schmidt S, Karreman C, Prisack JB, Bojar H, Baltzer AWA (2002) rIL-18 triggered gene therapy based on a transduction with the IL-12 plasmid: A new option as immuno-therapy for osteosarcoma? Anticancer Res 22: 2559-65 http://www.ncbi.nlm.nih.gov/pubmed/12529964

  20. Liebau C, Baltzer AW, Schmidt S, Roesel C, Karreman C, Prisack JB, Bojar H, Merk H (2002) Interleukin-12 and interleukin-18 induce indoleamine 2,3-dioxygenase (IDO) activity in human osteosarcoma cell lines independently from interferon-gamma. Anticancer Res 22: 931-6 http://www.ncbi.nlm.nih.gov/pubmed/12014674

  21. Baltzer A, Whalen J, Wooley P, Latterman C, Truchan L, Robbins P, Evans C (2001) Gene therapy for osteoporosis: evaluation in a murine ovariectomy model. Gene Ther 8: 1770-6 http://www.nature.com/gt/journal/v8/n23/full/3301594a.html

  22. Lattermann C, Baltzer AWA, Whalen JD, Niyibizi C, Evans CH, Fu FH (2001) Feasibility of adenoviral gene delivery to an atrophic non-union in a rabbit. The Pittsburgh Orthopaedic Journal 12: 274-276

  23. Lattermann C, Whalen JD, Baltzer AWA, Robbins PD, Niyibizi C, Evans CH, Fu FH (2001) Gene transfer to the tendon-bone insertion site. The Pittsburgh Orthopaedic Journal 12: 277-279 http://www.springerlink.com/content/7lu84n2h8x7cbcry/

  24. Baltzer AWA, Lattermann C, Weiss K, Wooley P, Grimm M, Ghivizzani SC, Robbins PD, Evans CH (2000) Genetic enhancement of fracture repair: Healing of an experimental segmental defect by adenoviral transfer of the bone morphogenetic protein-2 gene. Gene Ther: 734-739 http://www.nature.com/gt/journal/v7/n9/full/3301166a.html

  25. Baltzer AWA, Lattermann C, Whalen JD, Ghivizzani S, Wooley P, Krauspe R, Robbins PD, Evans CH (2000) Potential role of direct adenoviral gene transfer in enhancing fracture repair. Clin Orthop Rel Res 379S: 120-125 http://ovidsp.tx.ovid.com/sp-3.2.2/ovidweb.cgi?T=JS&PAGE=fulltext&D=ovft&AN=00003086-200010001-00016&NEWS=N&CSC=Y&CHANNEL=PubMed

  26. Baltzer AWA, Lattermann C, Whalen JD, Robbins PD, Evans CH (2000) Viral gene transfer based on Ad-BMP-2 induces bone formation in a segmental defect model. Osteosynthese International 7: 187-197

  27. Lattermann C, Baltzer AWA (2000) Verstärkung der Expression von Wachstumsfaktoren durch adenoviralen Gentransfer. Eine neue Methode zur Frakturbehandlung? Chirurg 71: 995-1000 http://www.springerlink.com/content/yluft2762nhqjm80/

  28. Koch H, Baltzer AWA, Liebau C, Evans CH, Robbins PD, Merk HR, Krauspe R (2000) Optionen für den Einsatz einer Gentherapie zur Behandlung von Knochentumoren. Osteologie 9: 200-205 http://verlag.hanshuber.com/Zeitschriften/Osteo/00/os0003.html#os0003_07

  29. Baltzer AWA, Whalen JD, Stefanovic-Racic M, Ziran B, Robbins RD, Evans CH. (1999) therapy of bone diseases. Acta Orthop Scand 70: 419-424

  30. Baltzer AWA, Liebau C (1999) Bone Morphogenetic Proteins – Bedeutung für die biologische Knochenheilung. Z Orthop 137: Oa 9-10 http://www.ncbi.nlm.nih.gov/pubmed/10441820

  31. Baltzer AWA, Whalen JD, Muzzonegro T, Georgescu HI, Robbins PD, Evans CH (1999). In vitro Transduktion humaner osteoblastärer Zellpopulationen mit retroviralen Vektoren. Z Rheum 58: 88-94 http://www.springerlink.com/content/cqk4gu1b3t1uhnk0/

  32. Baltzer AWA, Lattermann C, Whalen JD, Braunstein S, Robbins PD, Evans CH. (1999) A gene therapy approach to accelerate bone healing: Evaluation of gene expression in a New Zealand white rabbit model. Knee Surg Sports Traum Arthrosc 7: 197-202 http://www.springerlink.com/content/4a2rey1614rwyweg/

  33. Baltzer AWA, Reinecke J, Wehling P, Granrath M, Schulitz KP. (1999) Knochendichte und Knochenstoffwechsel unter dem Einfluß des Vitamin-D-Rezeptor-Allel-Polymorphismus in einem deutschen Untersuchungskollektiv. Z Orthop 137: 273-279 https://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1037406

  34. Reinecke J.; Koch H.; Meijer H.; Granrath M.; Schulitz K-P.; Wehling P. Current status of gene therapy for rheumatoid arthritis. BioDrugs. 1999 Feb;11(2):103-14. http://www.ingentaconnect.com/content/adis/bio/1999/00000011/00000002/art00004

  35. Niyibizi C, Baltzer AWA, Lattermann C, Oyama M, Whalen JD, Robbins PD, Evans CH. (1998) Potential role for gene therapy in augmentation of fracture healing. Clin Orthop Rel Res 355: S148-153

  36. Lattermann C, Baltzer AWA, Whalen JD, Evans CH, Robbins PD, Fu FH. (1998) Gene Therapy in Sports Medicine. Sports Medicine and Arthroscopy 6: 83-88

  37. Evans CH, Robbins P, Baltzer AWA, Reinecke J, Wehling P. (1996) Grundlagen der Gentherapie: Aktueller Stand der Forschung. Orthopäd Praxis 32: 790-794